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Effects typically appear within 30-60 minutes of administration and persist for 4-6 hours
Some patients may be trained to manage their own injections at home, but this should only be done with proper instruction and supervision
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Similar to scrapie, -synuclein pathology spreads in the peripheral and enteric nervous systems, then to CNS, whereas Alzheimers tau pathology propagates within the CNS only, beginning in the brainstem then involving cortical areas in a characteristic pattern (De La-Rocque et al., 2021)
This added precaution helps maximize its shelf life and potency
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